• Contains magnesium and vitamin D3 that contributes to the maintenance of bone and muscle function. 
• Magnesium helps to reduce fatigue, and is necessary for the optimal functioning of the nervous system.
• Optimal bone and muscle function depends on more than just calcium. MAG OSTEO contains the essential vitamins and minerals that are necessary to enable the absorption of calcium from your diet.

MAG OSTEO is formulated for the maintenance of optimal muscle and bone health.

We hear a lot about how important calcium is for our bone health. What isn’t as widely circulated is just how critical the right balance between calcium and magnesium is to maintain a healthy diet. A synergistic effect between several vitamins and minerals, including magnesium, vitamin D, vitamin K2, vitamin B6, vitamin C, potassium, zinc and boron is necessary for not only our bone health, but our overall health as well.

Maintaining healthy bones is not just about taking calcium via your diet or numerous supplements. Our cells should be able to utilize calcium for the right purpose with the presence of the necessary vitamins, minerals and trace elements! The bone health mechanisms within your body are complex, but an explanation as to how MAG OSTEO helps to enable and boost these mechanisms is easy!

Instructions

When the powder is mixed with hot water, the ionic magnesium citrate is formed as a result of a reaction between magnesium carbonate and citric acid. In addition to magnesium, MAG OSTEO also contains a number of other minerals, trace minerals such as potassium, zinc and boron, as well as vitamins C, B6, D3 and K2.

Contents

• Magnesium (magnesium carbonate) 375 mg
• Surfactant (citric acid)
• Potassium (potassium carbonate) 300 mg
• Vitamin C (ascorbic acid) 200 mg
• Zinc (zinc picolinate) 10 mg
• Boron (boric acid) 3 mg
• Vitamin K2 (vitamin K2-MK7 trans.) 75 μg
• Vitamin B6 (pyridoxine hydrochloride) 2 mg
• Vitamin D3 (vegan cholecalciferol from low) 20 μg
• Natural citrus aroma
• Stevioglycosides (E960)

Why should I use Magnesium?

• Magnesium is one of the most common minerals in the human body.
• Magnesium is calcium's "partner in crime".
• Calcium must use magnesium to form bone tissue with phosphorus.
• Magnesium contributes to a normal energy metabolism, as well as an optimal electrolyte balance.

Why choose magnesium citrate?

• There are many forms of magnesium and magnesium compounds. Magnesium citrate has been proven to have good bioavailability and absorption. (1, 2)
• Compared to other forms of magnesium, such as magnesium oxide, magnesium citrate has been found to be readily absorbable. (3, 4) 
• Clinical studies have demonstrated that magnesium citrate may have a positive effect on the regulation of insulin and blood glucose concentrations. (5)

Why should I use Vitamin K2?

• Vitamin K2 acts as a GPS for calcium, and helps to route calcium away from places where it does not belong in larger amounts - for example, our blood vessels. 
• Vitamin K2 works closely with vitamin D3 on optimal mineralization of our bones. Vitamin K2 stimulates bone-building cells and restricts the activity of bone-destroying cells. (6)
• Lack of vitamin K2 is associated with decreased bone mass, osteoporosis and increased risk of bone fracture. (6, 7)

Why should I use Vitamin D3?

• Vitamin D3 is absolutely essential for disease prevention and bone health. (8)
• Vitamin D3 contributes to the normal absorption and utilization of calcium and phosphorus.
• Lack of vitamin D3 is associated with a lower bone mineral density and degeneration of our skeleton. (8)
• Vitamin D3 is important for our muscle strength and immune system. (9)

Why should I use Potassium?

• Potassium is essential for basic cellular functions, such as bringing nutrients into and out of our cells, including our nerve cells and muscles. (10)
• Potassium restrics the kidneys from releasing excessive amounts of calcium. This allows for a smaller amount of calcium to be mobilized away from bones. (12)
• Potassium works with vitamin K2 to ensure optimal bone mineralization. A sufficient intake of potassium is associated with optimized bone health in women and elderly men. (13, 14)

Why should I use Boron?

• Boron stimulates the production of the active vitamin D3 (calcitriol)
• Boron has a positive effect on the activity of our bone-building cells (osteoblasts), as well as on our bone structure and strength. (10)
• A lack of Boron is associated with defects in growth and development of our skeleton. (15)

Why should I use Vitamin C?

• Vitamin C is required for the development of collagen in bone-building cells - collagen is an important component of our hard bone structure. (10)
• Vitamin C affects both the quality and the amount of collagen in our bones. (16) 
• Studies indicate that vitamin C has a positive effect on bone health and bone mineralization. (17)

Why should I use Vitamin B6?

• Vitamin B6 (pyridoxine) is part of the formation of collagen in our bone structure, and is an important nutrient for the maintenance of our bones.
• Studies have shown a connection between a lower intake of vitamin B6 and lower bone mineral density which can result in an increased risk of fracture. (18, 19)

Why should I use zinc?

• Zinc is required for optimal cell growth (10), and stimulates bone tissue formation. (15)
• Zinc may have a protective effect on the negative effects that heavy metal element exposure (such as cadmium and lead) may have on bone health. (15) 
• Adequate supply of zinc is necessary for optimal function of vitamin B6. (11) 

Why is there no calcium in MAG OSTEO?

• Research suggests that dietary supplements which contain calcium do not have a bone-healthy effect, which is contrary to popular understanding. (20, 21) 
• Studies that have looked at the correlation between calcium supplements and cardiovascular disease have shown that calcium intake from diet alone protects against cardiovascular disease, but that calcium supplements can in fact increase the risk of cardiovascular disease. (22, 23, 24) 
• In addition to being associated with an increased risk of cardiovascular disease, calcium supplementation is also associated with an increased risk of developing kidney stones. (25)
• Without the magnesium, vitamins and other vital nutrients that form MAG OSTEO, we cannot take advantage of the bone mineral effects of calcium.

Where do I find calcium in food?

The bioavailability of calcium in food is an expression of how well we absorb it and how well we can utilize it. Bioavailability can have a decisive influence on the amount of calcium-containing foods we need to consume (26). In addition to this, the ability of the intestine to absorb calcium from the diet plays an important role, which in itself is dependent on the support that the vitamins within MAG OSTEO provide. In Denmark, the official daily recommendations for calcium are 800 mg (27). As the table below shows, the best sources of calcium within your diet are not necessarily those that come from dairy products. This table highlights just a small snapshot of the calcium rich foods that help form a healthy diet, but it emphasizes an important point; It is possible to cover the recommended daily need for calcium from, for example, green vegetables, fish (small fish with bones) and possibly a little nuts.

Where can I find food rich in calcium (28)

1. Ranade, V. V., and J. C. Somberg. 2001. “Bioavailability and Pharmacokinetics of Magnesium After Administration of Magnesium Salts to Humans.” American Journal of Therapeutics 8 (5):345–57.
2. Aydın, Hasan, Oğuzhan Deyneli, Dilek Yavuz, Hülya Gözü, Nilgün Mutlu, Işık Kaygusuz, and Sema Akalın. 2009. “Short-Term Oral Magnesium Supplementation Suppresses Bone Turnover in Postmenopausal Osteoporotic Women.” Biological Trace Element Research 133 (2):136–43.
3. Walker, Ann F., Georgios Marakis, Samantha Christie, and Martyn Byng. 2003. “Mg Citrate Found More Bioavailable than Other Mg Preparations in a Randomised, Double-Blind Study.” Magnesium Research: Official Organ of the International Society for the Development of Research on Magnesium 16 (3):183–91.
4. Lindberg, J. S., M. M. Zobitz, J. R. Poindexter, and C. Y. Pak. 1990. “Magnesium Bioavailability from Magnesium Citrate and Magnesium Oxide.” Journal of the American College of Nutrition 9 (1):48–55.
5. Chacko, Sara A., James Sul, Yiqing Song, Xinmin Li, James LeBlanc, Yuko You, Anthony Butch, and Simin Liu. 2011. “Magnesium Supplementation, Metabolic and Inflammatory Markers, and Global Genomic and Proteomic Profiling: A Randomized, Double-Blind, Controlled, Crossover Trial in Overweight Individuals.” The American Journal of Clinical Nutrition 93 (2):463–73.
6. Schwalfenberg, Gerry Kurt. 2017. “Vitamins K1 and K2: The Emerging Group of Vitamins Required for Human Health.” Journal of Nutrition and Metabolism 2017 (June):6254836.
7. Vermeer, Cees. 2012. “Vitamin K: The Effect on Health beyond Coagulation - an Overview.” Food & Nutrition Research 56 (April). https://doi.org/10.3402/fnr.v56i0.5329.
8. Holick, Michael F. 2004. “Sunlight and Vitamin D for Bone Health and Prevention of Autoimmune Diseases, Cancers, and Cardiovascular Disease.” The American Journal of Clinical Nutrition 80 (6 Suppl):1678S – 88S.
9. Beaudart, Charlotte, Fanny Buckinx, Véronique Rabenda, Sophie Gillain, Etienne Cavalier, Justine Slomian, Jean Petermans, Jean-Yves Reginster, and Olivier Bruyère. 2014. “The Effects of Vitamin D on Skeletal Muscle Strength, Muscle Mass, and Muscle Power: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.” The Journal of Clinical Endocrinology and Metabolism 99 (11):4336–45.
10. Gropper, Sareen S., Jack L. Smith, and Timothy P. Carr. 2016a. Advanced Nutrition and Human Metabolism. Cengage Learning.
11. Catharine Ross, A. 2014. Modern Nutrition in Health and Disease. Lippincott Williams & Wilkins.
12. Office of the Surgeon General (US). 2010. Bone Health and Osteoporosis: A Report of the Surgeon General. Rockville (MD): Office of the Surgeon General (US).
13. Tucker, K. L., M. T. Hannan, H. Chen, L. A. Cupples, P. W. Wilson, and D. P. Kiel. 1999. “Potassium, Magnesium, and Fruit and Vegetable Intakes Are Associated with Greater Bone Mineral Density in Elderly Men and Women.” The American Journal of Clinical Nutrition 69 (4):727–36.
14. Zhu, K., A. Devine, and R. L. Prince. 2008. “The Effects of High Potassium Consumption on Bone Mineral Density in a Prospective Cohort Study of Elderly Postmenopausal Women.” Osteoporosis International: A Journal Established as Result of Cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20 (2):335–40.
15. Zofková, Ivana, Petra Nemcikova, and Petr Matucha. 2013. “Trace Elements and Bone Health.” Clinical Chemistry and Laboratory Medicine: CCLM / FESCC 0 (0):1–7.
16. Finck, Henriette, Andrew R. Hart, Amy Jennings, and Ailsa A. Welch. 2014. “Is There a Role for Vitamin C in Preventing Osteoporosis and Fractures? A Review of the Potential Underlying Mechanisms and Current Epidemiological Evidence.” Nutrition Research Reviews 27 (02):268–83.
17. Aghajanian, Patrick, Susan Hall, Montri D. Wongworawat, and Subburaman Mohan. 2015. “The Roles and Mechanisms of Actions of Vitamin C in Bone: New Developments.” Journal of Bone and Mineral Research: The Official Journal of the American Society for Bone and Mineral Research 30 (11):1945–55.
18. Yazdanpanah, Nahid, M. Carola Zillikens, Fernando Rivadeneira, Robert de Jong, Jan Lindemans, André G. Uitterlinden, Huibert A. P. Pols, and Joyce B. J. van Meurs. 2007. “Effect of Dietary B Vitamins on BMD and Risk of Fracture in Elderly Men and Women: The Rotterdam Study.” Bone 41 (6):987–94.
19. McLean, Robert R., Paul F. Jacques, Jacob Selhub, Lisa Fredman, Katherine L. Tucker, Elizabeth J. Samelson, Douglas P. Kiel, L. Adrienne Cupples, and Marian T. Hannan. 2008. “Plasma B Vitamins, Homocysteine, and Their Relation with Bone Loss and Hip Fracture in Elderly Men and Women.” The Journal of Clinical Endocrinology and Metabolism 93 (6):2206–12.
20. Anderson, J. J. B., K. J. Roggenkamp, and C. M. Suchindran. 2012. “Calcium Intakes and Femoral and Lumbar Bone Density of Elderly U.S. Men and Women: National Health and Nutrition Examination Survey 2005–2006 Analysis.” The Journal of Clinical Endocrinology and Metabolism 97 (12):4531–39.
21. Bischoff-Ferrari, Heike A., Bess Dawson-Hughes, John A. Baron, Peter Burckhardt, Ruifeng Li, Donna Spiegelman, Bonny Specker, et al. 2007a. “Calcium Intake and Hip Fracture Risk in Men and Women: A Meta-Analysis of Prospective Cohort Studies and Randomized Controlled Trials.” The American Journal of Clinical Nutrition 86 (6):1780–90.
22. Li, Kuanrong, Rudolf Kaaks, Jakob Linseisen, and Sabine Rohrmann. 2012. “Associations of Dietary Calcium Intake and Calcium Supplementation with Myocardial Infarction and Stroke Risk and Overall Cardiovascular Mortality in the Heidelberg Cohort of the European Prospective Investigation into Cancer and Nutrition Study (EPIC-Heidelberg).” Heart 98 (12):920–25.
23. Xiao, Qian, Rachel A. Murphy, Denise K. Houston, Tamara B. Harris, Wong-Ho Chow, and Yikyung Park. 2013. “Dietary and Supplemental Calcium Intake and Cardiovascular Disease Mortality: The National Institutes of Health-AARP Diet and Health Study.” JAMA Internal Medicine 173 (8):639–46.
24. Bolland, Mark J., Alison Avenell, John A. Baron, Andrew Grey, Graeme S. MacLennan, Greg D. Gamble, and Ian R. Reid. 2010a. “Effect of Calcium Supplements on Risk of Myocardial Infarction and Cardiovascular Events: Meta-Analysis.” BMJ 341 (July):c3691.
25. Favus, M. J. 2011. “The Risk of Kidney Stone Formation: The Form of Calcium Matters.” The American Journal of Clinical Nutrition 94 (1):5–6.
26. Guéguen, Léon, and Alain Pointillart. 2000. “The Bioavailability of Dietary Calcium.” Journal of the American College of Nutrition 19 (sup2):119S – 136S.
27. Nordic Council of Ministers, Nordic Council of Ministers, and Nordic Council of Ministers Nordic Council of Ministers. 2008. “Nordic Nutrition Recommendations 2012.” Nordic Nutrition Recommendations 2012 5 (11):1–3.
28. http://frida.fooddata.dk/ShowList.php?compid=108